Molecular Cell Biology Concentration

NOTE: This page is for detailed information about the Molecular Cell Biology Advanced Concentration only. All inquiries concerning admission to the BMS must be directed to the BMS Admissions office at biomed@med.ufl.edu. More information on admissions is also available on the Admissions Page.

Overview

The Advanced Concentration in Molecular Cell Biology is one of eight advanced concentrations leading to the Ph.D. degree under the auspices of the Graduate Program (BMS) in Biomedical Sciences at the University of Florida College of Medicine.

The Advanced Concentration in Molecular Cell Biology (MCB) prepares investigators for careers in biomedical research in academic or industrial settings. This multidisciplinary program has nearly 60 participating faculty members and offers an extraordinary range of opportunities for advanced study of life at the molecular and cellular levels.

Molecular Cell Biology provides the essential linkage between important basic fields of biomedical sciences, such as genetics, developmental biology, immunology, neurobiology and cancer biology. Cell biology has indeed matured from a descriptive discipline into one that is focusing on the elucidation of function at cellular and molecular levels. As we will soon have identified all the gene products that are potentially synthesized by an organism, it will be essential to connect sequence information to physiological function with the context of the cell.

Cell biology at the University of Florida is a highly interdisciplinary research area which is undergoing rapid growth in areas such as cell regulation and cancer, manipulation of stem cells, liver pathobiology, and the role of aberrant protein processing and trafficking in disease processes. Therefore, Molecular Cell Biology will be at the center of the new era of biomedical research.

Meet Eric Vitriol, Ph.D., assistant professor, and Mat Sebastian, M.D./Ph.D. student:


Areas of Research

The diverse faculty shares common interests in the molecular interactions that account for the functionally integrated subcellular, cellular and tissue organization found in living organisms. The model systems in use range from yeast and cellular slime molds through Drosophila to birds and mammals. These systems are manipulated and analyzed employing a wide range of powerful molecular, genetic, protein chemical, immunological, pharmacological, nuclear magnetic resonance (NMR) and microscopic imaging strategies.


Program of Study

MCB students must take the Advanced Cell Biology course (GMS 6421, 4 credit hours). After completion of the first year, MCB students must satisfactorily complete at least 6 credits of advanced elective graduate courses, including at least 3 credits of advanced MCB courses. GMS 6421 does not count towards advanced MCB credits, even if taken in the second year. An outside course can be used for an advanced MCB credit at an MCB concentration director’s advisement.

Beginning in the 2nd year, MCB students must register for the Journal Club (GMS 6690) and Data Club (GMS 6692) courses each fall and spring semester. These courses do not count towards the requirement of 3 credit hours of MCB advanced courses. Students are exempt from Journal Club and Data Club during the semester of their dissertation defense.

Supervisory Committees

The committee should be selected between 2-3 months after the student’s choice of mentor or by the end of the first summer term. The requirements for MCB supervisory committees are:

  • Four to six members (including chair)
  • At least one member from MCB concentration (primary or secondary) in addition to chair
  • One member must be external (outside MCB concentration)
  • At least one member must be a Full Professor
  • No more than two members may be Assistant Professors

Each student is required to consult with an MCB concentration director and receive their approval prior to finalizing their dissertation committee.

Supervisory Committee Meetings

Beginning in the 2nd year, MCB students must schedule supervisory committee meetings every six months, preferably in the fall and spring semesters. Following committee meetings, two administrative
tasks must be completed. These two tasks must be completed within one week of the committee meeting.

  • The student must deliver a completed and signed committee meeting form to the MCB graduate secretary.
  • The mentor must send a meeting summary and student progress report to the supervisory committee and the MCB graduate secretary. This summary and progress report should clearly state the committee’s assessment of the student’s academic and research progress.

One annual supervisory committee meeting may be virtual, if approved by the mentor and committee. For virtual committee meetings, students must provide supporting documents (e.g., PowerPoint presentation, manuscripts, etc.) to committee members at least one day in advance of the virtual meeting. Per BMS policy, a committee member, concentration director, or associate dean, has the authority to require, for any reason, that a committee meeting be held in person rather than virtually. The time between face‐to‐face meetings cannot exceed one calendar year.

Qualifying Examination

The written part of the qualifying exam will consist of a Biosketch, Specific Aims page, and Research Strategy in the format of an NIH F31 fellowship application. This must be delivered to the committee no later than one week before the scheduled oral exam.

As stated in the BMS Handbook, the qualifying exam will be given by an examination committee consisting of the supervisory committee plus an MCB director. The examination will be directed by a chair selected from the examination committee. The chair cannot be the primary mentor or MCB director. The chair will take notes, collect input from the examination committee, complete the BMS Qualifying Exam Form, and supervise completion of the UF Qualifying Exam Form. Both forms should be delivered to the MCB secretary within one day of the examination. An MCB Director is required to attend the Qualifying Exam. Students are responsible for coordinating with an MCB director when scheduling the exam.

The following guidelines pertain to outcomes that are neither Pass nor Fail:

Pass with remediation  The student, with assistance from the mentor, prepares a remediation plan that must be approved by the examination committee (committee members and an MCB director). The plan will be written and circulated to the committee within one week after the qualifying exam. Completion of remediation will be assessed at the first committee meeting after the exam. An MCB director must attend this meeting to confirm completion of the remediation plan.

Fail with option for re-examination  The student, with assistance from the mentor, must schedule a second qualifying examination. The second qualifying exam must be held before the end of the fall term of the third year of graduate studies.


The Faculty and their Research

For a list of faculty members in the Molecular Cell Biology advanced concentration, please click here.


Concentration Contacts