Immunology-Microbiology Journal Club

Fall 2012
Thursday, 12:00-1:00
LG-110 (also R2-265)

Director: Dr. L.J. Chang (

Please keep in mind that the article should represent a whole new and exciting discovery – a paradigm shift in our understanding of immunity and/or microbiology – preferably a combination of the two fields – NOT an incremental addition to an ongoing story.  It should not be so focused in its scope that only a few members of the journal club will find it interesting.

Tips on preparing and delivering a good presentation

Link to Anonymous Presentation Evaluation
Peer feedback is important.  Please complete this as soon as possible after the presentation.

Rubric for Journal Club Evaluations


Date Presenter Review* Article
23-Aug Organizational Meeting
30-Aug C. Lilly E. Sampson IFNγ Inhibits the Cytosolic Replication of Shigella flexneri via the Cytoplasmic RNA Sensor RIG-I
6-Sep R. Whitener H. Brown A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes.
13-Sep (R2-265) M. Kara D. Jacobs Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING
20-Sep (R2-265)  Cancelled  Cancelled
27-Sep (R2-265) Z. Moye TL Trinh TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification.
4-Oct  I. Velsko  M. Nelson Gut Immune Maturation Depends on Colonization with a Host-Specific Microbiota,
11-Oct TL Trinh L. Adamson  Acute Gastrointestinal Infection Induces Long-Lived Microbiota-Specific T Cell Responses;
18-Oct (R2-265) Rotation presentation 1
25-Oct YY Zheng A. Gauna Butler N.S. et al.  “Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection.”  Nature Immunology.  February 2012;
1-Nov C. Graves
A. Sang Priming of natural killer cells by nonmucosal mononuclear phagocytes requires instructive signals from commensal microbiota.
8-Nov R. Gross L. Gay The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB.
15-Nov S. Lamb K. Grau Hematopoietic-specific targeting of influenza A virus reveals replication requirements for induction of antiviral immune responses.
29-Nov E. Feldman A. Posgai Short-Range Exosomal Transfer of Viral RNA from Infected Cells to Plasmacytoid Dendritic Cells Triggers Innate Immunity.
6-Dec (R2-265) Rotation Presentation 2

*A student will be paired with the senior presenting student to review the presentation and PowerPoint BEFORE the journal club.  Please submit the review with your name (not optional) by Wednesday afternoon of the journal club presentation.  The reviewer must also submit a critique of the presentation as well.  This post-journal club critique should be submitted using the same feedback form as soon as possible after the presentation.